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There is a growing health and socioeconomic burden of obesity, with an increasing demand for effective anti-obesity drugs ideally comparable to bariatric surgery, the current gold-standard for obesity treatment which offers highly effective, long-lasting and life-extending results (4)

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[DOI] [PMC free article] [PubMed] [Google Scholar] Yun SP, Kam TI, Panicker N, Kim S, Oh Y, Park JS, Kwon SH, Park YJ, Karuppagounder SS, Park H, Kim S, Oh N, Kim NA, Lee S, Brahmachari S, Mao X, Lee JH, Kumar M, An D, Kang SU, et al

Patients at highest risk include those in the dose-escalation phase, experiencing active gastrointestinal symptoms (nausea, vomiting, bloating), those with known gastroparesis, or those taking concurrent medications that further delay gastric emptying (such as opioids)