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In August 2024, Novo Nordisk, one of the pharmaceutical leaders in diabetes and obesity care, launched its weight-loss drug Wegovy in Australia, intended for chronic weight management in patients with obesity or overweight with related conditions like diabetes or hypertension, Wegovy entered the market amid ongoing Ozempic supply concerns

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Among the lipid metabolism-related genes, Scd1 , Fabp4 , and Mogat2 were significantly upregulated in the WD-fed MC4R-KO mice

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