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Outcome measures Primary outcome measures included laboratory safety data, adverse event data and efficacy as measured by change from baseline Modified Hammersmith Functional Motor Scale (MHFMS) scores following six months of treatment versus placebo

The role of bile acids as aggressors in the intestinal cavity has been studied for many years to the point where no disease has been described in which bile acids are the primary initiator of injury

Sequence, chemistry, clinical evidence, FDA and anti-doping status, safety, and analytical recommendations reviewed in July 2026.

Regulation of gut microbiota and intestinal metabolites by poria cocos oligosaccharides improves glycolipid metabolism disturbance in high-fat diet-fed mice