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For tirzepatide, compounding became widely discussed during GLP-1 shortages because demand for Mounjaro and Zepbound outpaced supply

Jensen MH, Kjolby M, Hejlesen O, Jakobsen PE, Vestergaard P

Given the recognized window of opportunity in early PsA, future research should prioritize trials in patients with subclinical joint involvement, arthralgia, or early enthesitis, especially those with coexisting obesity or MetS