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This recommendation means that there's a population of women who stop using GLP-1s before pregnancy, raising questions about whether that can cause any negative effects

25,26 Therefore, starting with lower doses and a slower dose titration may help minimize this risk

Pre-filled pens for tirzepatide and semaglutide need refrigeration (28 C) until first use, and even after first use most stay stable at room temperature only for a limited window UK SmPCs allow up to 30 days at no more than 30 C for an in-use Mounjaro KwikPen, up to 56 days for an in-use Ozempic pen, and up to 28 days unrefrigerated for a Wegovy pre-filled pen

Elia AE, Bagella CF, Ferre F, Zorzi G, Calandrella D, Romito LM