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RAAS plays a vital role in ensuring stable hemodynamics by controlling the volume of extracellular fluid, maintaining sodium balance, optimizing tissue perfusion, and exerting trophic effects on cardiovascular system

doi:10.1016/j.jacl.2011.03.002

A narrative review conducted by Trujillo investigated the relative risks for associated adverse effects (such as GI symptoms, hypoglycemia, injection-site reactions, pancreatitis, neoplasms, gallbladder disease, and diabetic retinopathy) among three GLP-1 RAs when injected once weekly

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