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10.1016/S2213-8587(20)30075-9 Lancet Diabetes Endocrinol

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Limitations of a Symptom-Suppression Pain Model While medications and injections may reduce pain temporarily, they often: Do not correct structural imbalance or tissue degeneration Fail to resolve inflammatory or immune-driven pain Overlook metabolic contributors such as blood sugar instability or nutrient depletion Ignore nervous system sensitization and central pain amplification that perpetuate chronic pain As a result, pain frequently returnssometimes requiring higher doses, repeated injections, or additional medications to maintain relief