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When to Seek Medical Attention If you experience severe abdominal pain, persistent vomiting, or signs of dehydration while on GLP-1 therapy, contact your physician immediately

Much of an administered dose is swallowed but not absorbed, as shown by fecal excretion studies

doi:10.1177/0748233707077431

Several factors contribute to these elevated costs: Patent protection Most GLP-1 medications are still under patent, preventing generic competition Manufacturing complexity These are biologic medications that require specialized production processes Research and development costs Pharmaceutical companies invest heavily in clinical trials and regulatory approval Market positioning These medications are often priced as premium treatments Without insurance coverage, patients face the full retail price, which can make these medications financially inaccessible for many people who need them