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55 MiR-182-5p directly inhibits the expression of FOXO3a, preventing its binding to -catenin, enhancing the interaction between -catenin and TCF4, and then promoting canonical Wnt signalling
TB-500 (10 mg) A full-sequence Thymosin 4 peptide investigated in cell migration, actin dynamics, angiogenesis and tissue repair
Thymosin Beta-4: Actin-Binding Properties and Cellular Function. Annals of the New York Academy of Sciences, vol
Neurodevelopmental disorder-associated SNIP1 mutation E366G reduces binding to P-SF3B1 A homozygous SNIP1 mutation (E366G) found in ~ 35 individuals from the Amish population has been identified as the genetic cause of a neurodevelopmental disorder characterized by hypotonia, craniofacial abnormalities, and seizures (NEDHCS) 47,48
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