Kluck RM et al (1999) The pro-apoptotic proteins, bid and bax, cause a limited permeabilization of the mitochondrial outer membrane that is enhanced by cytosol
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L-carnitine has been approved by the US Food and Drug Administration for the treatment of PCD and SCD (76)
In studies reporting event counts, ALC arm events were mainly categorized as gastrointestinal (GI) and central nervous system (CNS), with other systems (skin/subcutaneous, urinary, cardiovascular, endocrine/metabolic, reproductive) reported infrequently