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Use of GLP-1 medications Source: Montero, et al KFF, November 14, 2025 KFF published survey data showing that one in 12 American adults report that they are currently taking GLP-1 medications

PCOS and Hormonal Imbalances Conditions like Polycystic Ovary Syndrome (PCOS) or thyroid disorders can drastically alter your hunger hormones, often leading to a stronger biological drive to eat that can overpower early doses of semaglutide

An absolute risk reduction of 1.4%

A retrospective cohort study using real-world data from 1845 elderly patients with T2DM found that GLP-1 RAs use was associated with a significantly lower risk of developing OP, even after adjusting for multiple confounders including age, sex, BMI, smoking, and antihypertensive use