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In a randomized controlled study, fortifying wheat with L-lysine resulted in decreased chronic anxiety in men and a reduced cortisol response to a stressful event in women

By methylating and removing nicotinamide, NNMT effectively drains NAD+ precursor availability, leading to reduced intracellular NAD+ levels

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At a 12 mg maintenance dose, researchers would use 2.4 mL per injection, requiring either larger syringes or split doses