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As for other core genes in ferroptosis, knockdown of ACSL4 inhibits microglia activation and subsequent production of proinflammatory cytokines, whereas inhibition of sirtuin 2 increases p53 expression and acetylation, exacerbating ferroptosis after TBI [143, 144]

[DOI] [PubMed] [Google Scholar] 101.EI Waly B., Macchi M., Cayre M., Durbec P

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