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Novo Nordisk submitted a New Drug Application to the FDA on December 18, 2025, with FDA review expected during 2026

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Vegans and Vegetarians If you follow a vegan or vegetarian diet, you are at a heightened risk of B12 deficiency

Common compounded formulations include: Tirzepatide with cyanocobalamin (B12) : Pink to red Tirzepatide with glycine and B12 : Pink to red (glycine does not affect color) Tirzepatide with methylcobalamin : Pink to red (similar shade to cyanocobalamin) Tirzepatide with niacinamide : Clear to very faint yellow (no B12 means no pink) Visual comparison table Notice that one factor remains constant across every formulation in that table: clarity