what is the difference between glp 1 and berberine vs GLP-1: Key Differences Explained Berberine and GLP-1 Together: Safety,

Physiological replacement of GLP-1 by exogenous administration had little effect, but this may underestimate the role of endogenous GLP-1 for insulin secretion, because intravenous administration bypasses important hepato-portal sensors for GLP-1 [63]

When evaluated with more sensitive and reliable 24-h continuous monitoring and in thorough QT studies, two of the long-acting GLP-1 RAs, liraglutide and albiglutide, were shown to cause a pronounced increase in the 24-h time-averaged mean HR from baseline of up to 610 bpm, while for dulaglutide and exenatide LAR, the increase in 24-h mean HR was 34 bpm [23, 24, 27,28,29,30]

The GLP-1 saga is an exciting, complex, and rapidly evolving field that demands our attention, critical thinking, and thoughtful discussion.

Acts as an agonist for MC1R, MC3R, MC4R, and MC5R