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Interactions between the GLP-1 pathway and addictive drugs, such as nicotine, opioids, and psychostimulants, have been demonstrated in rodents (Figure 3), and these are reviewed in the following sections

doi: 10.1016/j.fertnstert.2004.11.089 164 AokiVWEmeryBRLiuLCarrellDT

Research utilizing the Broad Institutes Connectivity Map indicates that GHK-Cu can influence over 31% of human genes, shifting them from a "diseased" or "aged" state toward a healthier, more youthful profile