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There were also limitations in this study

Indeed, such abnormal presence of mitochondria in circulating red blood cells causes increased oxygen consumption, ROS generation, and hemolysis in SCD patients 50,51

New Phytol 157:135143 Pucciariello C, Innocenti G, Van de Velde W, Lambert A, Hopkins J, Clment M, Ponchet M, Pauly N, Goormachtig S, Holsters M, Puppo A, Frendo P (2009) (Homo)glutathione depletion modulates host gene expression during the symbiotic interaction between Medicago truncatul a and Sinorhizobium meliloti