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doi: 10.1056/NEJMoa2032183

James Hewes, a Bristol consultant surgeon who also specialises in obesity and bariatric surgery, told the BBC: "Anecdotally, we are seeing more patients presenting with gallstones

CSF samples could be assessed by central or local laboratory, provided the local laboratory was part of the Alzheimers Association quality control program at the time of analysis

The dose is built up slowly over 16 weeks: 0.25 mg in weeks 1 to 4, then 0.5 mg, 1.0 mg, 1.7 mg, and from week 17 the maintenance dose of 2.4 mg once a week