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Although the exact mechanisms by which the gut microbiota causes or alters depression are not fully understood, the vast evidence from previous clinical and preclinical studies supports the hypothesis that the gut microbiota can affect the development of depression, mainly through the HPA axis, inflammation, and modify the abundance of BDNF

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Finally, BAT radiodensity, an indicator of BAT lipid content, was similar across conditions except for formoterol stimulation (-130.249.8 Hounsfield Units, that was lower than formoterol + nicotinic acid (-114.028.8 Hounsfield Units

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