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Research reveals that senescent cells show upregulation of pro-apoptotic initiators PUMA and BIM while anti-apoptotic guardian BCL-2 is reduced, suggesting these cells are ready to undergo apoptosis but the execution is restrained by the FOXO4-p53 interaction

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The mechanism by which homocysteine might increase CVD risk remains the subject of a great deal of research (28)

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As the drug showed a weight loss effect during research, the company shifted the target to obesity

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