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The brain has a higher energy demand than other tissues and contains many mitochondria to supply this energy

While CBP/p300 is a well-validated direct interaction partner of NRF2 with prominent functions at enhancers, we report that this interaction is not required for NRF2-dependent NSCLC cell growth, indicating that NRF2 can sustain sufficient transcriptional activity in the absence of CBP/p300 coactivation

Within the larger family of glycerophospholipids, phosphatidylcholine is further categorized as a phosphatidyl choline, meaning it has a choline molecule as its head group attached via a phosphodiester bond to the glycerol backbone

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