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A recent JAMA Surgery comparison of bariatric surgery and GLP-1 receptor agonists highlights why long-term treatment selection matters

Cardiovascular outcomes, long-term efficacy and safety In people with T2D and established cardiovascular disease, the international guidelines for T2D recommend the use of GLP-1 RA or sodium glucose co-transporters 2 inhibitors (SGLT-2i) as first-line treatment (independent of HbA1c), based on multiple trials demonstrating their cardio-renal benefits [109]

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Ventricular tachycardia and AF were reported in two subjects in the placebo group, while hypotension and UTIs were reported in two subjects in the treatment group