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Pancreatic cancer cells take up cystine to synthesize GSH, which in itself inhibits ferroptosis

Start with simple changes: eat antioxidant-rich foods like berries and leafy greens, add sulfur-rich vegetables such as broccoli and garlic, get 79 hours of sleep, manage stress, and avoid smoking, alcohol, and heavily processed foods

Yu L, Gan X, Liu X, An R (2017) Calcium oxalate crystals induces tight junction disruption in distal renal tubular epithelial cells by activating ROS/Akt/p38 MAPK signaling pathway

They then conducted a single-institution Phase I clinical trial of MET combination therapy in 13 patients receiving radiation therapy, and the median progression-free survival of newly diagnosed and relapsed disease was 10 and 4 months, respectively, suggesting the feasibility of metformin intervention in glioma treatment (59)