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Metabolic mediators of the effects of body-mass index, overweight, and obesity on coronary heart disease and stroke: a pooled analysis of 97 prospective cohorts with 1.8 million participants

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The peptide was first identified in 1973 by Loren Pickart during research on human plasma, where he observed that a small copper-peptide complex was present in younger blood samples at higher concentrations than in older ones

This work is supported by National Natural Science Foundation of China (82272899, 81902782, 81730030, 82203180), Research Funding from West China School/Hospital of Stomatology Sichuan University (No