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Because GH and IGF-1 are mitogenic they drive cell division patient selection carries real weight

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Bcl-2: B-cell lymphoma 2, Bcl-XL: B-cell lymphoma-extra large, cAMP: cyclic adenosine monophosphate, CREB: cAMP-response element-binding protein, FoxO1/O3: forkhead box transcription factor 1/3, GLP1R: glucagon-like peptide-1 receptor, GSK-3: glycogen synthase kinase-3, LTP: long-term potentiation, MAPK: mitogen-activated protein kinase, mTOR: mammalian target of rapamycin, NF-B: nuclear factor kappa B, PD: Parkinsons disease, PI3K: phosphoinositide 3-kinase, PKA: protein kinase A