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PGC-1 regulates DRP1 expression by enriching in the promoter region to downregulate DRP1 expression and further inhibits mitochondrial fission ( via deacetylating and activating OPA1 (Samant et al., 2014)

Psoriatic patients have a distinct structural and functional fecal microbiota compared with controls

The Fe 3 O 4 -PLGA-Ce 6 nanosystem, which dissociates in acidic TME, and the Fe 2+ -based metalorganic framework, which delivers Fe 2+ to cancer cells, can also promote the Fenton reaction and facilitate ferroptosis (Xu et al., 2020b

Nonetheless, researchers used a sibling control analysis to account for familial confounders, such as parents autistic traits