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Consistent with prior studies 4,24 , ACLY KO cells maintain lower levels of histone acetylation at H3K23 and H3K14 than their WT and ACSS2 KO counterparts, and DKO cells exhibit similar levels of acetylation as single ACLY KO cells (Figure 4A, B)

Intradermal injections of TXA, vitamin C, and glutathione were administered at weeks 2, 4, 6, and 8

Egecioglu, E., et al

This method of looking at the pros and cons is always the best way to look at any therapy but, when you do, make sure you take into account all pros and cons