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a non-oral method or additional barrier contraception during initiation and escalation may be advisable until more data are available

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Third, reverse-direction MR analysis between exogenous antioxidants and cancers was not performed in this study, considering the objectives of investigating the role of antioxidants in tumor prevention, the identification of non-causal relationships in forward-direction analysis, and the fact that exogenous antioxidants are supplemented mainly through dietary sources