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Because of that uncertainty, the FDA labelling recommends weighing the benefits of breastfeeding alongside the mother's need for Zepbound and any possible effects on the baby

Additionally, their larger size and chemical properties make it difficult for them to be absorbed through the intestinal wall into the bloodstream

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According to GoodRx, a company that operates a telemedicine platform that tracks drug prices and provides drug coupons for discounts, the number of people with no commercial insurance coverage for Zepbound (tirzepatide) increased by over 180% in 2025