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Diabetic retinopathy is classified into stages: Non-proliferative diabetic retinopathy (NPDR) : characterised by microaneurysms, haemorrhages, and exudates Proliferative diabetic retinopathy (PDR) : marked by neovascularisation and its complications Diabetic maculopathy/diabetic macular oedema (DMO) : involving the central retina (macula), affecting detailed vision Key risk factors include: Duration of diabetes (risk increases significantly after 1015 years) Poor glycaemic control (elevated HbA1c) Hypertension Dyslipidaemia Pregnancy Rapid improvement in blood glucose control (paradoxical early worsening) The NHS Diabetic Eye Screening Programme offers annual retinal photography to all people with diabetes aged 12 and over, enabling early detection and timely intervention

As litigation expanded, two separate federal multidistrict litigations (MDLs) were established in the Eastern District of Pennsylvania: one focused on gastrointestinal injuries and another involving NAION vision loss claims tied to semaglutide medications

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