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The ingredient for pH adjustment of products

Profound sedation, respiratory depression, coma, and death may result from the concomitant use of oxycodone and acetaminophen tablets with benzodiazepines and/or other CNS depressants, including alcohol [e.g., non-benzodiazepine sedatives/hypnotics, anxiolytics, tranquilizers, muscle relaxants, general anesthetics, antipsychotics, gabapentinoids (gabapentin or pregabalin), and other opioids]

Li S, Tan HY, Wang N, Zhang ZJ, Lao L, Wong CW, et al

318,319 One study revealed that CP31398 could facilitate the binding of mutant p53 to p53 response elements in vivo and restore the DNA-binding activity of mutant p53 in vitro