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However, most of the time when I see Botox done with general neurology or pain management, the techniques and patterns are not adequate, and the patients often dont respond

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Moreover, such endogenous brain proteins, cross-seeded to induce aggregation into toxic oligomers, could become the pernicious species responsible for growth of slowly expanding lesions in progressive MS, or form tiny islands of deposited seed to which microglia react to form nodules in pre-lesions

That assumption made sense before telehealth became mainstream