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Thyroid C-Cell Tumors - The risk of thyroid c-cell tumors (carcinomas and adenomas) had been exposed to rats and mice after Semaglutide treatment

And reacting at room temperature for 3h, adding 10mL of glacial methyl tert-ether, precipitating a white solid, centrifuging, adding methyl tert-ether into the product, washing for 3 times, washing for 2 times with 10mL of ethyl acetate, drying, and purifying by reversed-phase HPLC to obtain 84mg of semaglutide with the purity of 97.52%, wherein the specific liquid-phase chromatogram is shown in FIG

acylating refers to the introduction of one or more acyl groups covalently bonded to the free amino groups of the protein or peptide

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