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Although the molecular determinants stabilizing GPx-1 transcripts have not yet been identified, protein kinase C (PKC)-mediated pathways are essential for adenosine-mediated GPx-1 upregulation, as bisindolylmaleimide-1, a nonspecific PKC-inhibitor, blocked upregulation

HUBERMAN: So what these things are typically called are secretagogues

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The six-amino-acid structure (N-hexanoic-Tyr-Ile-(6) aminohexanoic amide) is susceptible to cleavage by pepsin and trypsin, meaning any dihexa that survives gastric pH is cleaved in the duodenum