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HER2 status was distributed as 0 in 56%, 1+ in 32%, 2+ in 6% and 3+ in 6%

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Importantly, their ability to undergo OXPHOS and to form tumors was effectively restored by genetic replacement of their mt-DNA [5]

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3 Molecular classification of breast cancer Pathologically, breast cancer is classified into two major categories: (i) breast invasive carcinoma, which accounts for 70-75% of the cases, and (ii) lobular carcinoma, accounting for 12-15% of the cases

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