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That means were shooting blind to some extent trying to use mitochondrial enhancers to affect the complex mitochondrial energy production

Tirzepatide, a dual GLP-1 and GIP receptor agonist, has shown efficacy in managing T2DM and obesity

We were also reassured by the absence of any signal for increased hospitalization or surgery, which are common concerns with medications that affect gastrointestinal function. If future studies confirm these results, he added, they could reassure clinicians that GLP-1 receptor agonists can be used safely in certain patients with Crohns disease who also have obesity or diabetes