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Usually, the answer is found in outcomesthe products, systems, or artifacts designers create

2016;7:110 Nature Publishing Group

Oxidative stress and chronic low-grade inflammation, in turn, exacerbate muscle catabolism and negatively affect functional capacity [4, 14]

Although pain mechanisms are different in neuropathic or nociceptive pain, vitamin B12 as a pain killer has had positive effects in these studies, similar to our studied FM patients [11, 12]