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Even if your other features are beautiful, a recessed chin can make the neck appear fuller, the jawline less defined, or the profile feel a little "off." Common characteristics of a weak or recessed chin include: Chin looks small, sloped, or short The profile appears imbalanced or "pulled back" The neck or under-chin area looks fuller than you'd like The jawline lacks that crisp definition The lower face appears round or soft Here's what surprises so many of our patients: the chin has an enormous impact on the entire face

Currently, there is no practical way to measure individual NNMT activity to predict response

Patients received either prophylactic treatment (n = 120) with ADYNOVATE at a dose of 40-50 IU per kg twice weekly or on-demand treatment (n = 17) with ADYNOVATE at a dose of 10-60 IU per kg for a 6-month period