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We recommend taking your medication as directed by your doctor and waiting at least 30 to 60 minutes before consuming anything else, including your collagen

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While each individuals experience varies, most clients notice improvements within the following general timeframes: Immediate Effects (2448 hours) Mild energy boost Slight improvement in mental clarity Sense of overall revitalization Many clients report feeling more alert and focused within the first day or two after a B12 shot, particularly if they were experiencing fatigue or low energy due to mild nutrient depletion

However, as Miller says, the research linking B12 with bone health only shows an association, not a cause-effect relationship