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Constipation and Diarrhea: Managing Opposite Digestive Extremes Semaglutide users experience either constipation or diarrheararely both simultaneouslybecause the medication's effects on gut motility vary among individuals
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Phase II neutralizes them by covalently attaching a conjugation group (glucuronic acid, glutathione, sulfate, acetyl, methyl, or amino acid) that increases polarity, reduces reactivity, and enables transport into bile or urine
Like any medication, Wegovy comes with important safety considerations, including possible side effects, serious risks, and certain conditions where it may not be safe to use
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