In another study, the RBCs stored with the GSH precursor amino acids, did not show any decrease in total GSH concentration from weeks 1 to 6
Kim S, An JN, Song YR, et al
The imbalance of the redox status mediated by folate deficiency or methionine load has been characterized by various indices of oxidation such as increases in end-products of lipid oxidation (conjugated dienes, hydroperoxides, and thiobarbituric acid reactive substances), changes in the fatty acid composition with decreased polyunsaturated fatty acids (mostly n-3 fatty acids), and a lower antioxidant defense, as demonstrated using the free radical-mediated erythrocyte hemolysis test described in Durand and Blache (1996) and in Prost (1992)
Since immune function is a systemic measure of general health, a higher IMMUNIDEX score is generally desired since it means a person can respond efficiently not only to exogenous threats such as pathogens or allergens, but also to endogenous threats like tumors