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Powdered tissue (5 g) was homogenized with chilled 50 mM sodium phosphate buffer (pH 8.0) containing 5 mM EDTA, centrifuged, and the supernatant was collected

Common risk factors for NAION include: Diabetes High blood pressure High cholesterol Sleep apnea Small or crowded optic nerves Smoking Cardiovascular disease Older age These risk factors are important because many patients who take GLP-1 medications may already have diabetes, obesity, sleep apnea, or vascular risk factors that can also increase NAION risk

As with any supplement, its best to consult a doctor before incorporating L-carnitine into your routine, says Allen