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The concept of methionine-dependent exocytosis was enunciated in the 1950s (77, 165, 166) and is now pinpointed to methylation of membrane components, probably of a prenylated cysteine residue (40)

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Surgical myocardial infarction Experimental myocardial infarction (MI) was induced via permanent ligation of the left anterior descending (LAD) coronary artery in 1012-week-old male mice as described previously [13]