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In females, PFOS demonstrated the highest PIP in the relationships between PFAS mixtures and LDL-C (PIP = 0.37) and TC (PIP = 0.38), whereas PFNA showed the highest PIP in the associations with TG (PIP = 0.84) and AIP (PIP = 0.65) (Table S3)

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Among these, 11 were ratios between E1 and its metabolites, which included methylated and hydroxylated E1, as well as some 16-OH pathway metabolites, E1 DNA-adducts, and E1 sulphate, glucuronide, and GSH conjugates