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Rymut N, Heinz J, Sadhu S, Hosseini Z, Riley CO, Marinello M, et al

The intraperitoneal administration of LPS, which is a cell wall component of gram-negative bacteria, such as Escherichia coli and Salmonella spp, increases intestinal permeability and causes the accumulation of phosphorylated -synuclein fibrils in the intestinal mucosa and dorsal vagal nuclei 27

These include: Hydroquinone (prescription only in Singapore): A well-studied tyrosinase inhibitor used to reduce focal hyperpigmentation

Beginning in late 2025, coverage will tighten to focus only on those with higher BMIs or qualifying medical conditions, leaving many individuals unsure whether their treatment will continue