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Natasha Bhuyan, MD, is a general practitioner and the vice president of in-office care at One Medical

Notably, no signal for ION was detected with tirzepatide, a dual GLP-1/GIP receptor agonist used for diabetes and obesity, and comparator drugs such as metformin and insulin also showed no significant associations

Visual inspection, physical characteristics, and functional assessment all contribute to degradation detection

This difference between clinical trial data and real-world experience makes it important for patients to communicate openly with their healthcare providers about any side effects they experience