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CJC-1295 (no DAC) is the GHRH-side component of choice for these combination studies because it preserves the pulsatile signalling that mimics physiological GH release patterns

Leptin is a key pro-inflammatory element in the pathogenic phase of SLE, as established by these processes taken together

The rationale: early-phase neuroplasticity benefits from sustained HGF/c-Met signaling, but once synaptic remodeling is initiated, daily pulses are sufficient to maintain the effect