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Studying GLP-1, GIP, and glucagon triple RA for the treatment of MASLD/MASH follows the success of mono- and dual-agonists helping patients with type 2 diabetes and obesity achieve clinical targets by offering advantages of each constitutive component while minimising the risk of undesirable effects

An exploratory analysis of genetic data of patients from the Clinical Antipsychotic Trials of Intervention Effectiveness (CATIE) trial showed that different haplotypes encoding for GLP-1R correlated with variable response rates to antipsychotic medications 132

24 Another study by Lenton et al 25 showed that vitamin C supplements increase glutathione in human lymphocytes