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Age-related egg quality decline is one of the most common fertility issues, alongside a low ovarian reserve, which refers to a reduced number of available eggs

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The FDA and major US medical organizations including the American College of Obstetricians and Gynecologists (ACOG), The Menopause Society (formerly NAMS), and the National Academies of Sciences, Engineering, and Medicine (NASEM) have concluded that claims describing compounded bioidentical hormone therapy as safer or more effective than FDA-approved hormone therapy are not supported by evidence from well-designed clinical studies