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show that NRF2-induced cystine uptake drives the formation of several cysteinesugar metabolites

Al-Majed AA, Sayed-Ahmed MM, Al-Yahya AA, Aleisa AM, Al-Rejaie SS, Al-Shabanah OA: Propionyl-L-carnitine prevents the progression of cisplatin-induced cardiomyopathy in a carnitine-depleted rat model

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PI3K/Akt/mTOR and MAPK Pathway Activation IGF-1R engagement activates two primary downstream signalling pathways: the PI3K/Akt/mTOR pathway, primarily responsible for protein synthesis, cell growth, and inhibition of protein breakdown